Methods and materials relating to prothrombinase-like...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 14/00 (2006.01) C07K 14/475 (2006.01) C07K 14/705 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/00 (2006.01) C12N 15/00 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12N 15/85 (2006.01) C12N 15/86 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2395749

The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel secreted prothrombinase-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human ovary (Hyseq clone identification numbers 773565 (SEQ ID NO: 1) and 7727065 (SEQ ID NO: 11)). Other aspects of the invention include vectors containing processes for producing novel secreted prothrombinase-like polypeptides, and antibodies specific for such polypeptides.

Cette invention se rapporte à de nouveaux polynucléotides et à des polypeptides codés par ces polynucléotides et à des mutants ou variants de ceux-ci, qui correspondent à un nouveau polypeptide de type prothrombinase sécrété. Ces polynucléotides comprennent des séquences d'acide nucléique isolées à partir d'une bibiothèque d'ADNc provenant de l'ovaire humain (numéros d'identification de clones Hyseq 773565 (SEQ ID NO: 1) et 7727065 (SEQ ID NO: 11)). D'autres aspects de cette invention concernent des vecteurs contenant des processus pour produire de nouveaux polypeptides de type prothrombinase sécrétés, et des anticorps spécifiques de ces polypeptides.

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