Substituted triazole derivatives as oxytocin antagonists

A - Human Necessities – 61 – K

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A61K 31/4439 (2006.01) A61K 31/4196 (2006.01) A61P 15/00 (2006.01) C07D 249/08 (2006.01) C07D 401/04 (2006.01) C07D 403/06 (2006.01) C07D 403/14 (2006.01)

Patent

CA 2602383

The present invention relates to a class of substituted triazoles of formula (I) with activity as oxytoci antagonists, uses thereof, processes for the preparation thereof and compositions containing sai inhibitors. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction particularly premature ejaculation (P.E.).

L'invention concerne une classe de triazoles substitués de formule (I) possédant une activité d'antagonistes d'oxytocine, des utilisations de ceux-ci, des procédés destinés à la préparation de ceux-ci et des compositions contenant ces inhibiteurs. Ces inhibiteurs possèdent une utilité dans une variété de domaines thérapeutiques notamment le dysfonctionnement sexuel, plus particulièrement l'éjaculation précoce (P.E.).

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