Chronic, bolus administration of d-threo methylphenidate

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/4458 (2006.01) A61K 31/445 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2468370

Chronic bolus administration of D-threo methylphenidate is provided. The administration of the n-threo isomer eliminates adverse side effects associated with the DL racemate, and provides improved effectiveness. The compositions and methods of the invention are useful in treating nervous system disorders including attention deficit disorder, attention deficit hyperactivity disorder, and cognitive decline associated with systemic diseases such as acquired immunodeficiency syndrome.

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