Methods of treating and diagnosing diabetes with cx3cr1...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/00 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/567 (2006.01) G01N 33/68 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2487438

The present invention provides compositions and methods for diagnosing and treating diabetes and insulin resistance. In particular, the invention provides methods of identifying modulators of CX3CR1 and using those modulators to treat diabetes, as well as methods of diagnosing diabetes by measuring the levels of CX3CR1 or fractalkine in a patient.

L'invention concerne des compositions et des méthodes permettant de diagnostiquer et de traiter le diabète et la résistance à l'insuline. L'invention concerne en particulier des méthodes permettant d'identifier des modulateurs de CX3CR1 et l'utilisation de ces modulateurs pour traiter le diabète ainsi que des méthodes permettant de diagnostiquer le diabète par mesure des niveaux de CX3CR1 ou de fractalkine chez un patient.

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