Sustained-release tramadol formulations with 24-hour...

Details Sustained-release tramadol formulations with 24-hour... Sustained-release tramadol formulations with 24-hour...

A - Human Necessities

61

K

A61K 31/137 (2006.01) A61K 9/22 (2006.01) A61K 9/24 (2006.01)

Patent

CA 2489855

There is disclosed a once daily oral pharmaceutical compositor for controlled release of tramadol or a salt thereof, wherein the composition, when ingested orally, provides a clinical effect over 24 hours which is a least as good as the clinical effect over 24 hours of two doses of a twice daily oral pharmaceutical composition for controlled release of tramadol, taken 12 hours apart

Composition pharmaceutique orale à prise quotidienne pour la libération prolongée de tramadol ou de l'un de ses sels, ladite composition, lorsqu'elle est prise par voie orale, ayant une efficacité clinique de 24 heures, laquelle est au moins équivalente à l'efficacité clinique sur 24 heures de deux doses, prises à intervalle de 12 heures, d'une composition pharmaceutique orale à prise biquotidienne pour la libération prolongée de tramadol.

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