Piperidine compounds as muscarinic antagonists

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 211/58 (2006.01) A61K 31/4545 (2006.01) A61P 25/28 (2006.01) C07D 211/22 (2006.01) C07D 211/24 (2006.01) C07D 401/06 (2006.01)

Patent

CA 2462861

The present invention discloses compounds, which are novel muscarinic receptor antagonists, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such muscarinic receptor antagonists as well as methods for using them to treat cognitive disorders such as Alzheimer's disease.

La présente invention concerne des composés constituant de nouveaux antagonistes des récepteurs muscariniques, ainsi que des méthodes de préparation de ces composés. Dans un autre mode de réalisation, l'invention concerne des compositions pharmaceutiques comprenant lesdits antagonistes des récepteurs muscariniques ainsi que des méthodes d'utilisation de celles-ci pour traiter les troubles cognitifs tels que la maladie d'Alzheimer.

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