Compositions and methods for stabilizing polymers

A - Human Necessities – 61 – K

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A61K 47/30 (2006.01) A61K 9/00 (2006.01) A61K 9/06 (2006.01) A61K 9/08 (2006.01) A61K 47/24 (2006.01) A61K 47/32 (2006.01) A61K 47/36 (2006.01) C08K 5/5317 (2006.01)

Patent

CA 2222646

Compositions and methods for reducing the decomposition rate of polymeric bioadhesives and viscosity enhancers, such as poly(acrylic acids). The compositions include at least one strong, stable chelating agent, preferably an organophosphorous compound such as diethylene triamine penta(methylene phosphonic acid). These biocompatible compositions are especially useful in the ophthalmic field.

La présente invention décrit des composés et des procédés permettant de diminuer le taux de décomposition des biocolles et stimulateurs de viscosité polymériques, tels que les poly(acides acryliques). Les compositions comportent au moins un fort agent chélatant stable, de préférence un composé organophosphorique tel que le diéthylène triamine penta(méthylène acide phosphonique). Ces compositions biocompatibles trouvent surtout leur usage dans le domaine de l'ophtalmologie.

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