The neurosteroid dhea as a marker for neuropathologies

Details The neurosteroid dhea as a marker for neuropathologies The neurosteroid dhea as a marker for neuropathologies

C - Chemistry, Metallurgy

12

Q

C12Q 1/16 (2006.01) A23J 1/00 (2006.01) C07H 21/04 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2398358

One of the major problems with the diagnosis and treatment of neurological diseases is the inability of clinicians to determine the onset of disease. The present invention describes methods and kits whereby the onset of neuropathology is detected by changes in the normal levels of neurosteroids, and particularly DHEA and its metabolic precursors, in the brain and serum.

L'un des principaux problèmes posés par le diagnostic et le traitement des affections neurologiques est l'incapacité dans laquelle se trouve le médecin de déterminer le point de départ de la maladie. Cette invention concerne des méthodes et des kits qui font intervenir des changements survenus dans les niveaux normaux de neurostéroïdes au niveau du cerveau et le sérum, en particulier de la DHEA et de ses neuroprécurseurs, pour détecter le point de départ d'une neuropathologie.

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