Novel sequence for improving expression of nucleic acid

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) C12N 15/67 (2006.01)

Patent

CA 2573022

The invention provides a novel anti-repressor element, which is useful for improving expression of nucleic acid in host cells. Methods using the novel anti-repressor element for producing a protein of interest are also provided. The invention also provides new configurations of expression cassettes comprising anti-repressor elements.

La présente invention concerne un nouvel élément anti-répresseur, qui convient particulièrement à l'amélioration de l'expression de l'acide nucléique dans des cellules hôtes. L'invention concerne également des procédés d'utilisation de ce nouvel élément anti-répresseur pour produire une protéine étudiée. L'invention concerne enfin de nouvelles configurations de cassettes d'expression comprenant les éléments anti-répresseurs.

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