Purine compounds and methods of use thereof

Details Purine compounds and methods of use thereof Purine compounds and methods of use thereof

C - Chemistry, Metallurgy

07

H

C07H 19/213 (2006.01) A61K 31/7076 (2006.01) A61P 3/00 (2006.01) A61P 9/00 (2006.01) A61P 25/00 (2006.01) C07H 19/16 (2006.01) C07H 19/19 (2006.01) C07H 19/167 (2006.01)

Patent

CA 2643503

The invention relates to Purine Compounds; compositions comprising an effective amount of a Purine Compound; and methods for reducing a subject's rate of metabolism or protecting a subject's heart against myocardial damage during cardioplegia; or for treating or preventing a cardiovascular disease, a neurological disorder, an ischemic condition, a reperfusion injury, obesity, a wasting disease, diabetes, a cellular proliferative disorder, a skin disorder, a radiation-induced injury, a wound or an inflammatory disease comprising administering an effective amount of a Purine Compound to a subject in need thereof.

La présente invention concerne des composés puriques ; des compositions comprenant une quantité efficace d'un composé purique ; et des procédés permettant de réduire la vitesse du métabolisme d'un sujet ou de protéger le cAEur d'un sujet contre les lésions myocardiques durant une cardioplégie ; ou des procédés destinés à traiter ou à prévenir une maladie cardiovasculaire, un trouble neurologique, un état ischémique, une lésion de reperfusion, l'obésité, une maladie cachectisante, un diabète, un trouble de prolifération cellulaire, une affection cutanée, une lésion induite par des rayonnements, une blessure ou une maladie inflammatoire, lesdits procédés comprenant l'administration d'une quantité efficace d'un composé purique à un sujet qui en a besoin.

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