Bioassay for polyq protein

G - Physics – 01 – N

Patent

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G01N 33/68 (2006.01)

Patent

CA 2732693

The present invention relates to bioassays for mutated polyQ protein associated with disease and their use as diag-nostic tools, for monitoring disease progression or for monitoring the efficacy of treatment of the disease. In a preferred embodi-ment the polyQ-protein is polyQ-huntingtin.

La présente invention porte sur des bioessais pour la protéine polyQ mutée associée à une maladie et sur leur utilisation en tant qu'outils de diagnostic, pour surveiller la progression d'une maladie ou l'efficacité du traitement de la maladie. Dans un mode de réalisation préféré, la protéine polyQ est la huntingtine polyQ.

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