Hydroxy methyl phenyl pyrazolyl urea compound useful in the...

Details Hydroxy methyl phenyl pyrazolyl urea compound useful in the... Hydroxy methyl phenyl pyrazolyl urea compound useful in the...

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4439 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01) A61P 35/04 (2006.01)

Patent

CA 2672951

The compound 4-{4-[({3-tert-Butyl-1-[3-(hydroxymethyl)phenyl]-1H-pyrazol-5-yl}carbamoyl)amino]-3-chlorohenoxy}-N-methylpyridine-2-carboxamide and alternativs forms thereof (e.g., salts, hydrates, solvates, prodrugs, polymorphs and metabolites); pharmaceutical compositions which contain them and methods for treating cancer using them.

L'invention concerne un composé de 4-{4-[({3-tert-Butyl-1-[3-(hydroxymethyl)phenyl]-1H-pyrazol-5-yl}carbamoyl)amino]-3-chlorohenoxy}-N-methylpyridine-2-carboxamide et des formes alternatives de celui-ci (par exemple, des sels, des hydrates, des solvats, des promédicaments, des polymorphes et des métabolites); des compositions pharmaceutiques contenant le composé et des formes alternatives de celui-ci; et des méthodes pour traiter un cancer au moyen du composés et des formes alternatives de celui-ci.

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