Pharmaceutical preparation for inhalation of an opioid

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/485 (2006.01) A61K 9/72 (2006.01) A61P 11/16 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2354576

The present invention relates to the inhalation of opioids, such as morphine, administered as a dry powder. Opioids administered as dry powder for inhalation are intended for local treatment in the respiratory tract, or for systemic treatment following absorption in the lungs and airways. Indications for opioids dry powder per inhalation include the treatment of dyspnoea and pain. Opioids as dry powder for inhalation may be administered with the use of an inhaler, which can be described as a multi-dose reservoir system such as the Cyclovent .TM., or a premetered single-dose system such as the Cyclohaler .TM., or a premetered disposable system as the Disphaler .TM..

L'invention concerne l'inhalation d'opioïdes, tels que la morphine, administrés sous forme d'une poudre sèche. Les opioïdes pour inhalation administrés sous forme d'une poudre sèche sont utilisés pour un traitement local des infections respiratoires, ou pour un traitement systémique après absorption dans les poumons et les voies aériennes. Les indications pour l'absorption de poudre sèche opioïde par inhalation sont le traitement de la dyspnée ou de la douleur. Ces opioïdes peuvent être administrés à l'aide d'un inhalateur du type système de réservoir multi-dose tel que le Cyclovent<TM>, système à dose unique tel que le Cyclohaler<TM>, ou système doseur jetable tel que le Disphaler<TM>.

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