Combination treatment with il-1ra and compounds that inhibit...

Details Combination treatment with il-1ra and compounds that inhibit... Combination treatment with il-1ra and compounds that inhibit...

A - Human Necessities

61

K

A61K 38/20 (2006.01) A61K 31/64 (2006.01) A61P 19/02 (2006.01)

Patent

CA 2383026

The invention relates to methods and compositions for treating and preventing interleukin 1 (IL-1) mediated disease states. The methods and compositions use an interleukin 1 receptor antagonist (IL-1ra) polypeptide or variant thereof in combination with a non-steroidal IL-1 processing and release inhibiting agent.

L'invention concerne des procédés et des compositions servant à traiter et à prévenir des maladies dans lesquelles interleukine 1 (IL-1) joue un rôle. Ces procédés et ces compositions mettent en application un polypeptide antagoniste (IL-1ra) du récepteur d'interleukine 1 ou une de ses variantes en combinaison avec un agent non stéroïde inhibant le traitement et la libération d'IL-1.

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