Tslp vaccine for the treatment of th2 mediated inflammatory...

Details Tslp vaccine for the treatment of th2 mediated inflammatory... Tslp vaccine for the treatment of th2 mediated inflammatory...

A - Human Necessities

61

K

A61K 39/385 (2006.01) A61K 38/19 (2006.01) C07K 14/52 (2006.01)

Patent

CA 2670460

The invention relates to compositions for the treatment of TH2 mediated inflammatory conditions. The compositions are vaccines comprising a non-primate TSLP or fragments thereof to be used as a vaccine to treat humans with excessive TH2 mediated inflammatory conditions. For the treatment of TH2 mediate inflammatory conditions in other non-human mammals the TSLP of the species to be vaccinated is being used as antigen.

L'invention concerne des compositions destinées au traitement de troubles inflammatoires induits par TH2. Ces compositions consistent en des vaccins contenant un TSLP non primate ou des fragments de celui-ci destiné à être utilisé en tant que vaccin afin de traiter des êtres humains présentant des troubles inflammatoires induits par un excès de TH2. Pour le traitement de troubles inflammatoires induits par TH2 chez les mammifères non humains, le TSLP des espèces à vacciner est utilisé en tant qu'antigène.

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