Treatment of infertility with camp-increasing compounds...

Details Treatment of infertility with camp-increasing compounds... Treatment of infertility with camp-increasing compounds...

A - Human Necessities

61

K

A61K 31/52 (2006.01) A61K 31/00 (2006.01) A61K 31/575 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2333320

The present invention relates to a pharmaceutical composition comprising c-AMP- increasing compounds in low dose and at least one meiosis-stimulating compound for the treatment of infertility and to the use of low dose c-AMP-increasing compounds alone or in combination with at least one meiosis-stimulating compound to increase the rate of fertilization in a mammal and for the preparation of medicaments. The preferred c-AMP-increasing compound is Hypoxanthine. The meiosis-stimulating compound is FF-MAS (4,4-dimethyl-5alpha- cholest-8,14,24-trien-3beta-ol).

L'invention concerne une composition pharmaceutique qui renferme des composés stimulant la production d'AMPc à faible dose et au moins un composé stimulant la méiose, et qui permet de traiter l'infertilité. Elle concerne également l'utilisation desdits composés stimulant la production d'AMPc, seuls ou associés à au moins un composé stimulant la méiose, afin d'augmenter le taux de fécondité chez un mammifère et de préparer des médicaments.

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