Steroid derivatives, pharmaceutical compositions containing...

Details Steroid derivatives, pharmaceutical compositions containing... Steroid derivatives, pharmaceutical compositions containing...

C - Chemistry, Metallurgy

07

J

C07J 41/00 (2006.01) A61K 31/56 (2006.01) C07J 9/00 (2006.01) C07J 17/00 (2006.01) C07J 31/00 (2006.01) C07J 43/00 (2006.01) C07J 51/00 (2006.01)

Patent

CA 2157594

Compounds having a broad range of antimicrobial activity generally have a structure including a steroid nucleus with a cationic, preferably polyamine, side chain (X) and an anionic side chain (Y). The invention is also directed to compounds of formula (III) preferably where the steroid ring nucleus is saturated; the steroid ring substitutent Z5 is .alpha.-H; one Z7 is .beta.-H and the other is .alpha.-H or .alpha.-OH; both substituents Z12 are hydrogen; X' is a polyamine side chain of the formula -NH-(CH2)?-NH- (CH2)?-N(RII)(RIII) where p and q are each independently 3 or 4, and RII and RIII are each independently hydrogen or methyl; R' is methyl; and Y' is (C1-C10)-alkyl substituted with a group such as -CO2H or -SO3H.

Affiliated with

Also associated with

Rating

Steroid derivatives, pharmaceutical compositions containing... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Steroid derivatives, pharmaceutical compositions containing..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Steroid derivatives, pharmaceutical compositions containing... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1780764