Sustained release, and comfortable ophthalmic composition...

Details Sustained release, and comfortable ophthalmic composition... Sustained release, and comfortable ophthalmic composition...

A - Human Necessities

61

K

A61K 31/795 (2006.01) A61K 9/00 (2006.01) A61K 31/135 (2006.01) A61K 31/138 (2006.01) A61K 31/215 (2006.01) A61K 31/216 (2006.01) A61K 31/78 (2006.01) A61K 47/32 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2345466

Numerous drugs cause "stinging" as a side effect when used in the eye, thus increasing patient's discomfort, partly due to the presence of preservatives present in ocular formulations. The present invention is related to a new sustained release ophthalmic formulations with reduced stinging comprising a) at least one basic active; b) a polyanionic polymer; c) an ion exchange resin; and d) a pH adjusting agent. The present invention is also directed to the use of such formulations.

L'invention concerne des formulation ophtalmiques à libération prolongée et à pouvoir de picotement réduit. Elle concerne également des méthodes de traitement consistant à administrer de telles formulations, de manière topique, sur l'oeil, lorsque le besoin s'en fait ressentir.

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