Compositions and methods for treating cardiovascular,...

A - Human Necessities – 61 – K

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A61K 45/06 (2006.01) A61K 31/22 (2006.01) A61K 31/366 (2006.01) A61K 31/40 (2006.01) A61K 31/404 (2006.01) A61K 31/505 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2640615

Disclosed are compositions having one or more statins from two different groups, 1) one or more lipophilic statins and 2) one or more hydrophilic statins. The present invention is also directed towards methods of treating patients with cardiovascular diseases and other vascular diseases, including but not limited to Diabetes Mellitus type I and/or II (DM), coronary artery diseases (CAD), peripheral vascular diseases (PVD), cerebrovascular disease, post myocardial infarctions (post MI), post cerebrovascular accidents (post CVA), Hypertriglyceridemia, Hypercholesterolemia, and abdominal aortic aneurysms (AAA) using the composition of the present invention.

L'invention concerne des compositions qui ont une ou plusieurs statines provenant de deux groupes différents, 1) une ou plusieurs statines lipophiles et 2) une ou plusieurs statines hydrophiles. La présente invention concerne aussi des méthodes pour traiter des patients atteints de maladies cardiovasculaires et d'autres maladies vasculaires, y compris mais sans limitation le diabète sucré (DM) de type I et/ou II, des maladies coronariennes (CAD), des acrosyndromes (PVD), une maladie cérébrovasculaire, un syndrome post-infarctus du myocarde (post MI), un syndrome post-accidents cérébrovasculaires (post CVA), une hypertriglycéridémie, une hypercholestérolémie et des anévrismes de l'aorte abdominale (AAA) au moyen de la composition selon la présente invention.

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