N-thiazol-2-yl-benzamide derivatives

Details N-thiazol-2-yl-benzamide derivatives N-thiazol-2-yl-benzamide derivatives

C - Chemistry, Metallurgy

07

D

C07D 277/46 (2006.01) A61K 31/426 (2006.01) A61P 25/16 (2006.01)

Patent

CA 2542816

The invention relates to N-thiazol-2-yl-benzamide derivatives of the formula I in the description wherein the variables are as defined in the claims. The compounds are A2A-receptor ligands, such as antagonists, agonists, reverse agonists or partial agonists, and are useful in the treatment of neurological and psychiatric disorders where an A2A-receptor is implicated.

L'invention concerne des composés de formule (I), dans laquelle les variables sont telles que définies dans les revendications. Ces composés sont des ligands du récepteur A¿2A?, tels que des antagonistes, des agonistes, des agonistes inverses ou des agonistes partiels, et ils sont utiles dans le traitement de troubles neurologiques et psychiatriques où un récepteur A¿2A? est impliqué.

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