Treatment of bacterial infections

Details Treatment of bacterial infections Treatment of bacterial infections

A - Human Necessities

61

K

A61K 38/10 (2006.01) A61K 31/04 (2006.01) A61K 38/17 (2006.01)

Patent

CA 2554486

The invention relates to polypeptides, comprising repeats of peptides derived from apolipoproteins, which exhibit antibacterial activity and to nucleic acids encoding the same. The invention further provides the use of such polypeptides, derivatives, analogues or nucleic acids as medicaments, and also their use in methods of preventing or treating bacterial infection or objects and surfaces. The invention further extends to objects, such as contact lenses, coated with the polypeptides.

L'invention porte sur des polypeptides comprenant des unités de répétition de peptides dérives des apolipoprotéines et qui présentent une activité antibactérienne et sur des acides nucléiques les codant. L'invention porte également sur l'utilisation de ces polypeptides, sur des dérivés, des analogues ou des acides nucléiques utiles comme médicaments, et également sur leur utilisation dans des méthodes de prévention ou de traitement d'infections bactériennes ou d'objets et de surfaces. L'invention porte, en outre, sur des objets tels que des lentilles de contact recouvertes de ces polypeptides.

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