C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/42 (2006.01) A61K 39/395 (2006.01) A61P 37/00 (2006.01)
Patent
CA 2441048
The present invention relates to a novel drug candidate having a potential for universal therapy of allergy and asthma. The invention provides a Fab (antibody fragment), having the following characteristics: a) inhibits the IgE- Fc.epsilon.RI interaction; b) binds to free and cell-bound IgE; and c) is non- anaphylactic.
L'invention concerne un nouveau candidat-médicament doté d'un potentiel de thérapie universelle des allergies et de l'asthme. L'invention concerne notamment un Fab (fragment d'anticorps) doté des caractéristiques suivantes : a) inhibe l'interaction IgE-Fc.epsilon.RI, b) se lie à des IgE libres à liés à des cellules et c) est non anaphylactique.
Adriansson Jonas
Groenlund Hans
Hoegbom Erik
Kraft Dietrich
Laffer Sylvia
Fetherstonhaugh & Co.
Phadia Ab
Pharmacia Diagnostics Ab
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