A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4045 (2006.01) A61K 31/517 (2006.01) A61P 25/06 (2006.01)
Patent
CA 2520930
The invention relates to a method for the treatment or prevention of headaches, migraines or cluster headaches, said method including the combined administration of a therapeutically active quantity of the hydrochloride of the active ingredient base 1-[N2-[3,5-dibromo-N-[[4-(3,4-dihydro-2(1H)- oxoquinazolin-3-yl)-1-piperidinyl]-carbonyl]-D-tyrosyl]-L-lysyl]-4-(4- pyridinyl)-piperazine (A) and a therapeutically active quantity of the migraine active ingredient sumatriptan or a physiologically compatible salt thereof. The invention also relates to the corresponding pharmaceutical compositions and to the production of the same.
Méthode de traitement ou de prévention des céphalées, des migraines ou de la céphalée vasculaire de Horton, qui consiste à administrer de manière combinée une quantité thérapeutiquement efficace d'hydrochlorure de la base de principe actif 1-[N?2¿-[3,5-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-pipéridinyl]-carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-pipérazine (A) et une quantité thérapeutiquement efficace du principe actif contre la migraine sumatriptane ou d'un sel physiologiquement compatible de ladite substance. La présente invention concerne encore les compositions pharmaceutiques correspondantes ainsi que leur production.
Doods Henri
Eberlein Wolfgang
Rudolf Klaus
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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