Use of an epidermal growth factor receptor kinase inhibitor...

Details Use of an epidermal growth factor receptor kinase inhibitor... Use of an epidermal growth factor receptor kinase inhibitor...

A - Human Necessities

61

K

A61K 31/47 (2006.01) A61K 31/4706 (2006.01) A61K 31/4709 (2006.01) A61K 31/5377 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2646257

This invention discloses method of treating or inhibiting cancer in a human having at least one of an Exon 19 del E746-A750 and/or an Exon 21 point mutation comprising administering to said human gefitinib and/or iressa alone or in combination with other cytotoxic agents or chemotherapeutic agents and an effective amount of EGFR kinase inhibitor.

L'invention concerne une méthode de traitement ou d'inhibition du cancer chez un humain qui présente au moins une mutation ponctuelle de l'exon 19 del E746-A750 et/ou de l'exon 21, et qui consiste à lui administrer le gefitinib et/ou l'iressa seul ou combiné à d'autres agents cytotoxiques ou chimiothérapeutiques, ainsi qu'une dose efficace d'un inhibiteur kinase du EGFR.

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