Irreversible inhibitors of tyrosine kinases

Details Irreversible inhibitors of tyrosine kinases Irreversible inhibitors of tyrosine kinases

C - Chemistry, Metallurgy

07

D

C07D 239/94 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) A61K 31/55 (2006.01) A61K 31/675 (2006.01) C07D 403/04 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 495/04 (2006.01) C07D 521/00 (2006.01) C07F 9/6512 (2006.01) C07F 9/6558 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 2249446

The present invention provides compounds that are irreversible inhibitors of tyrosine kinases. Also provided is a method of treating cancer, restenosis, atherosclerosis, endometriosis, and psoriasis and a pharmaceutical composition that comprises a compound that is an irreversible inhibitor of tyrosine kinases.

La présente invention concerne des composés qui sont des inhibiteurs irréversibles de tyrosine kinases. L'invention, qui concerne également un traitement du cancer, de la resténose, de l'athérosclérose, de l'endométriose et du psoriasis, concerne en outre une spécialité pharmaceutique comprenant un composé qui est un inhibiteur irréversible de tyrosine kinases.

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