Fluorinated hydroxyalkylquinoline acids as leukotriene...

Details Fluorinated hydroxyalkylquinoline acids as leukotriene... Fluorinated hydroxyalkylquinoline acids as leukotriene...

C - Chemistry, Metallurgy

07

D

C07D 215/18 (2006.01) A61K 31/47 (2006.01)

Patent

CA 2092896

Compounds having the formula I: (see formula I) are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.

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