C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/78 (2006.01) A61K 31/435 (2006.01) A61K 31/50 (2006.01) C07D 213/81 (2006.01) C07D 213/82 (2006.01) C07D 213/89 (2006.01) C07D 215/48 (2006.01) C07D 217/26 (2006.01) C07D 237/24 (2006.01) C07D 237/28 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01) C07D 471/04 (2006.01) C07D 491/048 (2006.01) C07D 495/04 (2006.01) C07K 5/078 (2006.01)
Patent
CA 2134865
Abstract of the description Substituted heterocyclic carboxamide esters, their preparation and their use as pharmaceuticals The invention relates to compounds of the formula I, Image (I) to a process for their preparations and to their use as pharmaceuticals. The compounds are employed, in particu- lar, as ester prodrugs of prolyl hydroxylate inhibitors for inhibiting collagen biosynthesis and as fibro- suppressive agents.
Baringhaus Karl-Heinz
Bickel Martin
Tschank Georg
Weidmann Klaus
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Fibrogen Inc.
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