C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/16 (2006.01) A61K 38/22 (2006.01) C07K 1/02 (2006.01) C07K 14/585 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) G01N 33/50 (2006.01) G01N 33/74 (2006.01)
Patent
CA 2328783
The invention relates to human procalcitonin and the preparation and use thereof. In particular, a process for preparing human procalcitonin is described wherein a gene coding for a polypeptide comprising the amino acid sequence of human procalcitonin is inserted into a vector; a host organism is transformed with this gene- containing vector; and the polypeptide expressed by the host organism is isolated. Furthermore the use of the polypeptides according to the invention, in particular as medicaments and diagnostic agents is described.
L'invention porte sur la procalcitonine humaine ainsi que la préparation et l'utilisation de celle- ci. En particulier, on décrit un procédé de préparation de la procalcitonine humaine dans lequel un gène codant un polypeptide ayant la séquence en acides aminés de la procalcitonine humaine est inséré dans un vecteur. Un organisme hôte est transformé à l'aide de ce vecteur contenant ce gène. Le polypeptide exprimé par l'organisme hôte est isolé. En outre, on décrit l'utilisation du polypeptide de l'invention, en particulier en tant que médicament et agent diagnostique.
Althaus Harald
Hauser Hans-Peter
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Dade Behring Marburg Gmbh
Siemens Healthcare Diagnostics Products Gmbh
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