C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/073 (2010.01) C12N 5/071 (2010.01) A61K 35/39 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2404313
The invention discloses a substantially pure population of human pancreatic progenitor cells and methods of isolating and culturing the pancreatic progenitor cells. By carefully manipulating the microenvironment of the pancreatic progenitor cells, multiple passages are attainable wherein the pancreatic progenitor cells do not senesce and furthermore, are capable of becoming functional exocrine or endocrine cells. In addition, several methods of use of human pancreatic progenitor cells are disclosed herein.
L'invention se rapporte à une population sensiblement pure de cellules souches pancréatiques humaines et à des procédés d'isolement et de culture de ces cellules souches pancréatiques. Grâce à une manipulation minutieuse de l'environnement des cellules souches pancréatiques, il est possible de réaliser de multiples passages au cours desquels ces cellules souches pancréatiques ne vieillissent pas et peuvent, de plus, devenir des cellules fonctionnelles endocrines ou exocrines. En outre, l'invention se rapporte à plusieurs procédés d'utilisation de cellules souches pancréatiques humaines.
Mather Jennie Powell
Roberts Penelope E.
Borden Ladner Gervais Llp
Raven Biotechnologies Inc.
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