Treatments and prevention of hydrocephalus

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/519 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2695844

The present invention relates to the prevention or treatment of hydrocephalus. In one embodiment, the invention includes the use of one or more bioavailable folate derivatives, or salts thereof, for the prevention or treatment of hydrocephalus. Examples of more bioavailable folate derivatives that may be used include any combination of: folinic acid, tetrahydrofolate, thymidine, 10-formyltetrahydrofolate or methyltetrahydrofolate, or salts thereof. The invention also relates to a composition comprising two or more bioavailable folate derivative(s); for example, folinic acid and tetrahydrofolate.

La présente invention porte sur la prévention ou le traitement d'une hydrocéphalie. Dans un mode de réalisation, l'invention comprend l'utilisation d'un ou plusieurs dérivés du folate biodisponibles, ou des sels de ceux-ci, pour la prévention ou le traitement de l'hydrocéphalie. Des exemples de dérivés du folate davantage biodisponibles pouvant être utilisés comprennent toute combinaison de : acide folinique, tétrahydrofolate, thymidine, 10-formyltétrahydrofolate ou méthyltétrahydrofolate, ou des sels de ceux-ci. L'invention porte également sur une composition comprenant deux dérivés du folate biodisponibles ou plus, par exemple, l'acide folinique et le tétrahydrofolate.

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