Transgenic animals bearing human iglambda light chain genes

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/13 (2006.01) C12N 5/0735 (2010.01) A01K 67/027 (2006.01) C07K 16/00 (2006.01) C07K 16/46 (2006.01) C12N 5/10 (2006.01) C12N 15/08 (2006.01) C12N 15/09 (2006.01) C12N 15/85 (2006.01) C12N 15/87 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2468565

The invention relates to transgenic animals bearing one or more human .lambda. light chain loci. The invention also relates to methods and compositions for making transgenic animals that have incorporated human .lambda. light chain loci. The invention further relates to methods of using and compositions derived from the transgenic animals that have incorporated human .lambda. light chain loci.

Cette invention, qui a trait à des animaux transgéniques porteurs d'un ou de plusieurs loci .lambda. humains à chaîne légère, porte également sur des procédés, et les compositions correspondantes, permettant de produire des animaux transgéniques chez qui ont été introduits les loci .lambda. humains à chaîne légère. Elle concerne également des procédés d'utilisation ainsi que des compositions issues de ces animaux transgéniques chez qui ont été introduits les loci .lambda. humains à chaîne légère.

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