A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) C12N 5/071 (2010.01) A61K 31/7105 (2006.01) A61K 31/711 (2006.01) A61K 35/44 (2006.01) A61K 35/76 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) A61P 27/02 (2006.01) A61P 43/00 (2006.01) C07K 14/47 (2006.01) C12N 15/12 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2514971
A medical drug characterized by containing Otx2 protein, its partial peptide or a salt thereof (a), or a DNA or RNA coding for Otx2 protein or its partial peptide (b). This medical drug is useful as a preventive, curative or progress suppressor of retinal diseases such as retinal degeneration. Also, this medical drug is useful as an inducer of differentiation, for example, from retinal stem cells to retinal visual cells in the transplantation of cells into the retina, etc. of patients suffering from retinal diseases.
La présente invention concerne un médicament caractérisé en ce qu'il contient la protéine Otx2, sa partie peptide, ou l'un de ses sels (a) ou un ADN ou ARN codant pour la protéine Otx2 ou pour sa partie peptide (b). Ce médicament est indiqué pour prévenir, soigner ou arrêter l'évolution d'affections rétiniennes telles que la dégénérescence rétinienne. Ce médicament convient également comme inducteur de la différentiation, par exemple, pour donner des cellules visuelles de la rétine à partir de cellules souches de la rétine aux fins de transplantation de cellules dans la rétine, notamment de patients atteints d'affections rétiniennes.
Fetherstonhaugh & Co.
Japan Science And Technology Agency
Osaka Bioscience Institute
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