Method for producing solid preparation

Details Method for producing solid preparation Method for producing solid preparation

A - Human Necessities

61

K

A61K 31/4365 (2006.01) A61K 9/20 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2672157

Disclosed is a method for producing a solid preparation containing a compound represented by the general formula (I) below or a pharmacologically acceptable salt thereof and having improved dissolvability. Specifically disclosed is a method for producing a solid preparation containing a compound represented by the general formula (I) below or a pharmacologically acceptable salt thereof, which comprises a step wherein a composition containing a compound represented by the general formula (I) below or a pharmacologically acceptable salt thereof is mixed, while applying a mechanical stress to the composition.

L'invention concerne un procédé de production d'une préparation solide contenant un composé représenté par la formule générale (I) ou un sel pharmacologiquement acceptable de celui-ci, et présentant une dissolubilité améliorée. Plus particulièrement, l'invention concerne un procédé de production d'une préparation solide contenant un composé représenté par la formule générale (I) ou un sel pharmacologiquement acceptable de celui-ci, consistant à mélanger une composition contenant un composé représenté par la formule générale (I) ou un sel pharmacologiquement acceptable de celui-ci, et, parallèlement, à soumettre cette composition à une contrainte mécanique.

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