Specific binding agents

Details Specific binding agents Specific binding agents

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) C07K 16/18 (2006.01) C07K 16/30 (2006.01) C07K 16/46 (2006.01) C07K 19/00 (2006.01) C12N 1/21 (2006.01) C12P 21/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2090961

a reshaped human antibody or reshaped human antibody fragment having specificity for human polymorphic epithelial mucin.(PEM) is produced. by transferring the complementarity determining regions (CDRs) from a murine anti-HMFG hybridoma cell line HMFG1 into a human antibody variable region framework. The reshaped molecule can be used in the treatment or diagnosis of cancer,

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