Substituted diketopiperazine analogs for use as drug...

Details Substituted diketopiperazine analogs for use as drug... Substituted diketopiperazine analogs for use as drug...

C - Chemistry, Metallurgy

07

D

C07D 241/08 (2006.01) A61K 31/495 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2748490

Disclosed are drug delivery systems for the delivery of small molecule and macromolecular drugs. More particularly, disclosed are substituted analogs of 3,6-di(alkyl-4 aminobutyl)-2,5- diketopiperazine (which may also be referred to DKP), their use in the formulation of both small molecule and macromolecular drugs including therapeutic, prophylactic and diagnostic agents, stabilizing agents and systems for their delivery.

L'invention porte sur des systèmes d'administration de médicaments pour l'administration de médicaments à petites molécules et macromoléculaires. Plus particulièrement, l'invention porte sur des analogues substitués de 3,6-di(alkyl-4 aminobutyl)-2,5-dicétopipérazine (qui peut également être appelée DCP), sur leur utilisation pour la formulation de médicaments à la fois à petites molécules et macromoléculaires comprenant des agents thérapeutiques, prophylactiques et diagnostiques, des agents stabilisants, et sur des systèmes permettant leur administration.

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