Secreted polypeptides and corresponding polynucleotides

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 14/475 (2006.01) C07K 14/50 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2374053

The present invention provides novel polypeptides, termed SECX polypeptides, as well as polynucleotides encoding SECX polypeptides and antibodies that immunospecifically bind to SECX or a derivative, variant, mutant, or fragment of the SECX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the SECX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as to other uses.

L'invention concerne de nouveaux polypeptides, appelés polypeptides SECX, ainsi que des polynucléotides codant pour les polypeptides et les anticorps SECX qui se lient de façon immunospécifique à SECX ou à un dérivé, à un variant, à un mutant ou à un fragment du polypeptide, du polynucléotide ou de l'anticorps SECX. L'invention concerne également des procédés selon lesquels le polypeptide, le polynucléotide et l'anticorps SECX sont utilisés dans la détection et le traitement d'un large éventail d'états pathologiques, ainsi qu'à d'autres fins.

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