Benzofuranyl alkanamine derivatives and uses thereof as...

Details Benzofuranyl alkanamine derivatives and uses thereof as... Benzofuranyl alkanamine derivatives and uses thereof as...

C - Chemistry, Metallurgy

07

D

C07D 307/82 (2006.01) A61K 31/343 (2006.01) C07D 307/81 (2006.01)

Patent

CA 2605554

Compounds of formula I pr pharmaceutically acceptable salts thereof are provided: wherein each of R1, R1~ , R2, R3, R4, n, and Ar are as defined in the description which are agonists or partial agonists of the 2C subtype of brain serotonin receptors. The compounds, and compositions containing the compounds, can be used to treat a variety of central nervous system disorders such as schizophrenia.

La présente invention concerne des composés de formule I ou leurs sels acceptables sur le plan pharmaceutique: où chacun de R1, R1~ , R2, R3, R4, n, et Ar sont comme définis dans la description, qui sont des agonistes ou des agonistes partiels du sous-type 2C des récepteurs de la sérotonine du cerveau. Les composés, et les compositions contenant les composés, peuvent être utilisés pour traiter une variété de trouble du système nerveux central tels que la schizophrénie.

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