Use of an immuno complex for the preparation of a...

Details Use of an immuno complex for the preparation of a... Use of an immuno complex for the preparation of a...

C - Chemistry, Metallurgy

12

N

C12N 15/87 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2349404

Described is the use of an immuno complex, which comprises at least one antibody or a reactive part thereof and at least one polynucleotide, for the preparation of a therapeutic composition for the introduction of a polynucleotide into a macropinocyte target cell wherein said immuno complex has a particle size selected between 0.5 µm and 6 µm.

La présente invention concerne l'utilisation d'un immuno-complexe comprenant au moins un anticorps ou une partie réactive de cet anticorps et au moins un polynucléotide, pour la préparation d'une composition thérapeutique permettant l'introduction d'un polynucléotide dans une cellule cible macropinocyte, ledit immuno-complexe ayant une dimension des particules sélectionnée entre 0,5 µm et 6 µm.

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