A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/52 (2006.01) A61K 9/20 (2006.01) A61K 9/22 (2006.01) A61K 9/52 (2006.01) A61K 31/522 (2006.01) A61K 47/30 (2006.01) A61K 9/50 (2006.01)
Patent
CA 2304110
A sustained-release theophylline tablet prepared by coating granules consisting mainly of theophylline with at least one layer of either a coating film comprising a hydrophobic substance and a plastic excipient or a coating film comprising these ingredients and an enteric high-molecular substance to form coated granules and compacting the coated granules into a tablet together with a disintegrable excipient.
L'invention concerne un comprimé de théophylline à libération prolongée préparé par enrobage de granules constitués essentiellement de théophylline avec au moins une couche soit d'un film d'enrobage comprenant une substance hydrophobe et un excipient plastique, soit d'un film d'enrobage comprenant ces ingrédients ainsi qu'une substance entérique de masse moléculaire élevée pour former des granules enrobés, et par compactage des granules enrobés en un comprimé avec un excipient désintégrable.
Kamakura Minoru
Okumura Mutsuo
Sunohara Masaaki
Borden Ladner Gervais Llp
Nikken Chemicals Co. Ltd.
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