N-heteroaryl-purin-6-amines, a process for their preparation...

Details N-heteroaryl-purin-6-amines, a process for their preparation... N-heteroaryl-purin-6-amines, a process for their preparation...

C - Chemistry, Metallurgy

07

D

167/202, 167/220

C07D 473/34 (2006.01) A61K 31/52 (2006.01) A61K 31/70 (2006.01) C07H 17/02 (2006.01) C07H 19/16 (2006.01)

Patent

CA 2018563

This invention relates to a N-heteroaryl-purin-6-amine of the formula (see formula I), where R1 is hydrogen, lower alkyl, and arylloweralkyl; R2 and R3 are independently hydrogen, lower alkyl or R2 and R3 taken together are aryl; R4 and R5 are independently hydrogen, lower alkyl, or R4 and R5 taken together are aryl; R6 is hydrogen, lower alkyl, aryl, arylloweralkyl, (see formula II), and (see formula III), where R2, R3, R4 and R5 are as defined above, and the pharmaceutically acceptable acid addition salts thereof sand where applicable the geometric and optical isomers and racemic mixtures thereof. The compounds of this invention display utility as analgesic and anticonvulsant agents.

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