Vitamin d analogues

Details Vitamin d analogues Vitamin d analogues

C - Chemistry, Metallurgy

07

C

C07C 401/00 (2006.01) A61K 31/59 (2006.01) C07B 59/00 (2006.01)

Patent

CA 2131631

2131631 9401398 PCTABS00030 The invention relates to compounds of formula (I), in which formula X is hydrogen or hydroxy; R1 and R2 stand for hydrogen or a C1-C6 hydrocarbyl radical; or taken together with the carbon atom bearing the group X, can form a C3-C8 carbocyclic ring; Q is a single bond or a C1-C8 hydrocarbylene diradical. R1, R2, and/or Q may be optionally substituted with one or more deuterium or fluorine atoms; and derivatives thereof. The compounds show anti-inflammatory and immunomodulating effects as well as strong activity in inducing differentiation and inhibiting undesirable proliferation of certain cells.

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