Stabilized carbapenem intermediates and synthetic use

Details Stabilized carbapenem intermediates and synthetic use Stabilized carbapenem intermediates and synthetic use

C - Chemistry, Metallurgy

07

D

C07D 477/20 (2006.01)

Patent

CA 2293835

A stabilized carbapenem intermediate compound represented by formula (1) or a salt thereof is disclosed, wherein P represents a carboxyl protecting group and X represents a charge balancing group. In addition, a process for synthesizing a compound represented by formula (2) is disclosed wherein X+ is a charge balancing group, comprising: deprotecting a compound of formula (1) to produce a compound (2).

L'invention concerne un composé intermédiaire stabilisé de carbapenem représenté par la formule (1), ou un sel de ce composé. Dans la formule (1), P représente un groupe protecteur carboxyle et X représente un groupe compensateur de charge. L'invention concerne également un procédé permettant la synthèse d'un composé représenté par la formule (2), dans laquelle X?+¿ est un groupe compensateur de charge. Ledit procédé consiste à déprotéger un composé de formule (1) pour produire un composé de formule (2).

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