Method of determining risk of scoliosis

G - Physics – 01 – N

Patent

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G01N 33/53 (2006.01) A61K 33/04 (2006.01) A61K 45/00 (2006.01) A61P 19/08 (2006.01) C07K 14/52 (2006.01) C07K 14/705 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/543 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2682114

A method for determining the risk for developing a scoliosis comprising monitoring osteopontin (OPN) expression in a sample from a subject over time; wherein an OPN expression that increases in the subject sample over time is indicative that the subject is at risk for developing a scoliosis.

L'invention concerne un procédé pour déterminer le risque de développer une scoliose, le procédé comprenant la surveillance de l'expression de l'ostéopontine (OPN) au cours du temps dans un échantillon provenant d'un sujet ; une expression d'OPN qui augmente au cours du temps dans l'échantillon du sujet est indicatrice que le sujet risque de développer une scoliose.

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