Screening method for evaluation of bilayer-drug interaction...

A - Human Necessities – 61 – K

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A61K 9/127 (2006.01)

Patent

CA 2540582

A method for generating a correlation between at least one thermal property of a liposomal carrier in the presence of a therapeutic agent and a pharmacokinetic property for the therapeutic agent in the liposomal carrier and using the correlation for predicting the pharmacokinetic property of the liposomal carrier in the presence of any therapeutic agent in a liposomal carrier.

L'invention concerne un procédé consistant à générer une corrélation entre au moins une propriété thermique d'un support liposomique en présence d'un agent thérapeutique et une propriété pharmacocinétique pour l'agent thérapeutique présent dans le support liposomique, et à utiliser cette corrélation pour prévoir la propriété pharmacocinétique du support liposomique en présence d'un agent thérapeutique quelconque se trouvant dans le support liposomique.

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