Enantiomeric enrichment and stereoselective synthesis of...

Details Enantiomeric enrichment and stereoselective synthesis of... Enantiomeric enrichment and stereoselective synthesis of...

C - Chemistry, Metallurgy

12

P

195/134

C12P 41/00 (2006.01) C12N 9/10 (2006.01) C12P 7/26 (2006.01)

Patent

CA 2018773

Amines in which the amino group is on a secondary carbon atom which is chirally substituted can be enantiomerically enriched by the action of an omega-amino acid transaminase which has the property of preferentially converting one of the two chiral forms to a ketone. The process also can be used to stereoselectively synthesize one chiral form from ketones substantially to the exclusion of the other.

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