Methods and compositions for the treatment of autoimmune...

Details Methods and compositions for the treatment of autoimmune... Methods and compositions for the treatment of autoimmune...

A - Human Necessities

01

N

A01N 63/00 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2306062

The invention relates to methods and compositions for the treatment of autoimmune disease. Specifically, compositions comprising heat shock proteins, including gp96, hsp90, and hsp70, are disclosed. Immunotherapeutic methods for administering the hsp-containing compositions are disclosed. Furthermore, methods for preventing rejection of organs transplanted to treat autoimmune disease are disclosed. The disclosed methods are useful for treating a variety of autoimmune diseases, including insulin dependent diabetes mellitus.

L'invention porte sur des procédés et compositions pour le traitement de maladies auto-immunes et spécialement sur des compositions contenant des protéines de choc thermique dont la gp96, la hsp90 et la hsp70, sur des procédés d'immunothérapie par administration de compositions contenant la hsp90, sur des procédés empêchant le rejet d'organes transplantés et traitant un ensemble de maladies auto-immunes dont le diabète sucré insulino-dépendant.

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