Anti-inflammatory compositions and combinations

A - Human Necessities – 61 – K

Patent

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Details

A61K 45/06 (2006.01) A61K 31/4015 (2006.01) A61K 31/4412 (2006.01) A61K 31/55 (2006.01) A61K 31/573 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2708352

The invention relates to the use of Broad-Spectrum Chemokine Inhibitors (BSCIs), and in particular members of the acylaminolactam class of pharmaceutical agents, for the prevention, prophylaxis, treatment or amelioration of symptoms of inflammatory diseases. In particular, improved compositions consisting of BSCI agents combined with one or more additional active pharmaceutical agents in order to achieve improved anti- inflammatory efficacy with a reduced side-effect profile are described and claimed.

La présente invention concerne l'utilisation d'inhibiteurs de chimiokine à large spectre (ICLS), et en particulier de certains agents pharmaceutiques appartenant à la classe des acylaminolactames, pour la prévention, la prophylaxie, le traitement ou l'atténuation de symptômes de maladies inflammatoires. L'invention concerne en particulier des compositions améliorées à base d'agents ICLS associés à un ou plusieurs autres agents pharmaceutiques actifs en vue d'obtenir une meilleure efficacité anti-inflammatoire assortie d'un profil d'effets secondaires réduits.

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