C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/41 (2006.01) A61K 31/4178 (2006.01) A61K 31/4439 (2006.01) A61K 31/4709 (2006.01) A61K 31/4725 (2006.01) A61K 31/495 (2006.01) A61K 31/53 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) C07D 401/06 (2006.01) C07D 403/06 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 411/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 419/14 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01) C07D 47
Patent
CA 2313106
This invention provides a compound of the following formula: Image or the pharmaceutically acceptable salts thereof wherein Z is tetrazolyl optionally substituted with a substituent selected from C1-4 alkyl and halosubstituted C1- 4 alkyl; A is C1-6 alkylene; Q is selected from the following groups: (a) optionally substituted phenyl; (b) an optionally substituted, partially saturated, fully saturated or fully unsaturated five to six membered monocyclic group having one to three heteroatoms; and (c) an optionally substituted, bicyclic group consisting of two fused partially saturated, fully saturated or fully unsaturated five or six membered rings independently and optionally having one to four heteroatoms; X is halogen, C1-4 alkyl, halosubstituted C1-4 alkyl, OH, C1-4 alkoxy or the like; and n is 0, 1, 2, 3 or 4. This invention also provides a pharmaceutical composition useful for the treatment of a medical condition in which prostaglandins are implicated as pathogens.
Nakao Kazunari
Stevens Rodney William
Bereskin & Parr
Pfizer Inc.
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