Prevention of loss and restoration of bone mass by certain...

Details Prevention of loss and restoration of bone mass by certain... Prevention of loss and restoration of bone mass by certain...

C - Chemistry, Metallurgy

07

C

C07C 311/06 (2006.01) A61K 31/16 (2006.01) A61K 31/18 (2006.01) A61K 45/06 (2006.01) C07C 59/90 (2006.01) C07C 235/34 (2006.01) C07C 311/04 (2006.01) C07C 317/44 (2006.01) C07C 323/25 (2006.01) C07C 323/49 (2006.01) C07C 323/59 (2006.01) C07D 207/26 (2006.01) C07D 207/263 (2006.01) C07D 209/14 (2006.01) C07D 213/42 (2006.01) C07D 215/12 (2006.01) C07D 215/18 (2006.01) C07D 239/26 (2006.01) C07D 241/12 (2006.01) C07D 249/06 (2006.01) C07D 249/08 (2006.01) C07D 257/04 (2006.01) C07D 271/12 (2006.01) C07D 277/

Patent

CA 2275479

Prostaglandin agonists of formula (I), in which, for example, A is a sulphonyl or acyl group, B is N or CH, M contains a ring and K and Q are linking groups, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits useful for the treatment of bone disorders including osteoporosis.

L'invention concerne des agonistes de la prostaglandine, correspondant à la formule (I), dans laquelle, par exemple, A représente un groupe sulfonyle ou acyle, B représente N ou CH, M contient un noyau, un K et Q représentent des groupes de liaison. L'invention concerne également des procédés d'utilisation de tels agonistes de la prostaglandine, des compositions pharmaceutiques contenant de tels agonistes et des nécessaires pouvant être utilisés pour le traitement d'affections des os, y compris l'ostéoporose.

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