A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/54 (2006.01) A61K 31/395 (2006.01) A61K 31/415 (2006.01) A61P 9/10 (2006.01)
Patent
CA 2439920
The invention includes methods for treating atherosclerosis and preventing atherosclerotic disease events in a hypertensive patient comprising administering to the patient a therapeutically or prophylactically effective amount of at least one antihypertensive compound in combination with a therapeutically effective amount of a cholesterol absorption inhibitor. The invention also includes a composition comprising at least one antihypertensive compound and a cholesterol absorption inhibitor in therapeutically effective amounts, and a pharmaceutically acceptable carrier.
L'invention concerne des méthodes de traitement de l'athérosclérose et de prévention des maladies athérosclérotiques chez un patient hypertendu. Ces méthodes consistent à administrer au patient une dose thérapeutiquement ou préventivement efficace d'au moins un composé antihypertenseur combinée avec une dose thérapeutiquement efficace d'un inhibiteur de l'absorption du cholestérol. L'invention concerne également une composition renfermant au moins un composé antihypertenseur et un inhibiteur de l'absorption du cholestérol en doses thérapeutiquement efficaces, ainsi qu'un substrat pharmaceutiquement acceptable.
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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